Osprey is a census-designated place (CDP) in Sarasota County, Florida, United States. The population was 6,690 at the 2020 census, up from 6,100 at the 2010 census. It is part of the North Port–Bradenton–Sarasota, Florida Metropolitan Statistical Area.

Osprey is home to Historic Spanish Point, a 30-acre (12 ha) museum and environmental complex that includes a prehistoric shell mound, a turn-of-the-century pioneer homestead museum, a citrus packing house, chapel, boatyard, gardens and nature trails. The Osprey Public Library is located at Historic Spanish Point and is part of the Sarasota County Public Library System.

Osprey is the mailing address for Oscar Scherer State Park and the new Scherer Thaxton Preserve, two of the few protected areas maintaining habitat for the threatened Florida scrub jay. Osprey is also the location of the Blackburn Point Bridge, a one-lane bridge over the Intracoastal Waterway that is listed on the National Register of Historic Places.

Osprey is also the site of an unsolved 1959 family massacre.